When we think about hair loss, many of us simply consider it an inevitable part of aging. However, the process is more complex than it seems, involving intricate biology and genetics. Understanding the science behind hair loss can help demystify the condition and enable better decisions about treatment options.
Human hair follows a continuous cycle of growth and rest that comprises four stages: anagen (growth phase), catagen (transitional phase), telogen (resting phase), and exogen (shedding phase). At any given time, most hair follicles are in the anagen phase, growing new hair, while a smaller portion are in the telogen or exogen stages.
In a typical scalp, 80-90% of hair follicles are in the anagen phase, while 10-20% are in the telogen phase. Every day, it's normal to shed 50 to 100 hairs in the exogen stage. But when something disrupts this balance—such as hormonal changes, genetics, or stress—the number of hairs in the telogen phase can increase, leading to noticeable hair loss.
Dihydrotestosterone (DHT) is a hormone derived from testosterone that plays a major role in hair loss, especially male pattern baldness (androgenetic alopecia). In individuals genetically predisposed to hair loss, hair follicles are sensitive to DHT. Over time, exposure to DHT causes these susceptible follicles to shrink, leading to a shorter hair growth cycle and thinner, shorter hairs. Eventually, these affected follicles may stop producing hair entirely.
Genetics is a significant factor in hair loss, with both mother's and father's sides contributing to an individual's likelihood of experiencing it. While the specific genes involved are still being studied, it's clear that hair loss tends to run in families. Researchers believe multiple genes, not just a single 'baldness' gene, influence the pattern and extent of hair loss.
Apart from DHT and genetics, other factors can contribute to hair loss. Telogen effluvium, for example, is a temporary form of hair loss triggered by stress, nutritional deficiency, or major life events like childbirth. Alopecia areata, on the other hand, is an autoimmune disorder where the body's immune system attacks its own hair follicles.
Furthermore, certain medical treatments, like chemotherapy, can lead to hair loss, as can tight hairstyles that pull on the hair (traction alopecia) or harsh hair care products that damage the scalp and follicles.
The science behind hair loss is complex, involving a myriad of genetic, hormonal, and environmental factors. But understanding this biology can make the process seem less daunting and more manageable. If you're experiencing hair loss, consider seeking advice from a healthcare provider and use tools like the Hairly app to track your progress over time. Remember, you're not alone in this journey, and a better understanding of the science behind hair loss can empower you to take positive steps towards managing your hair health.